揭開癌症的根源

最近的證據挑戰了長期以來關於細胞如何轉變為惡性的理論——並提出了在腫瘤擴散前阻止它們的新方法

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Aneuploidy Precedes and Segregates with Chemical Carcinogenesis. Peter Duesberg, Ruhong Li, David Rasnick, Charlotte Rausch, Andreas Willer, Alwin Kraemer, George Yerganian and Ruediger Hehlmann in Cancer Genetics and Cytogenetics, Vol. 119, No. 2, pages 83-93; June 2000.

Chromosome Segregation and Cancer: Cutting through the Mystery. Prasad V. Jallepalli and Cristoph Lengauer in Nature Reviews Cancer, Vol. 1, No. 2, pages 109-117; November 2001.

Rules for Making Human Tumor Cells. William C. Hahn and Robert A. Weinberg in New England Journal of Medicine, Vol. 347, No. 20, pages 1593-1603; November 14, 2002.

Multiple Mutations and Cancer. Lawrence A. Loeb, Keith R. Loeb and Jon P. Anderson in Proceedings of the National Academy of Sciences USA, Vol. 100, No. 3, pages 776-781; February 4, 2003.

W. Wayt Gibbs is a contributing editor for 大眾科學 based in Seattle. He also works as a scientific editor at Intellectual Ventures.

More by W. Wayt Gibbs
大眾科學 Magazine Vol 289 Issue 1This article was originally published with the title “Untangling the Roots of Cancer” in 大眾科學 Magazine Vol. 289 No. 1 ()
doi:10.1038/scientificamerican072003-6BMnQ2PyGvy0wPgkseeJii
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