藥物大幅降低心臟病發作風險

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科學家在治療心臟病方面邁出了重要一步。新的研究表明,對於經歷急性胸痛的患者,在標準療法中加入獲得許可的血液稀釋藥物氯吡格雷,可以將死亡、心臟病發作和中風的風險降低近 20%。這項研究的結果於週一在美國心臟病學會於佛羅里達州奧蘭多舉行的會議上公佈,表明該藥物每年可以挽救數千名美國人的生命。

在一項針對 28 個國家超過 12,500 名患者的研究中,安大略省漢密爾頓市麥克馬斯特大學的團隊負責人 Salim Yusuf 及其同事檢查了氯吡格雷對一種危及生命的疾病——急性冠狀動脈綜合徵的影響。一半的參與者在標準療法的基礎上每天服用一劑氯吡格雷,另一半則僅接受標準療法。研究小組發現,氯吡格雷組的心臟病發作減少了 23%,中風減少了 15%。

氯吡格雷由賽諾菲-聖德拉堡以波立維 (Plavix) 的名義銷售,由百時美施貴寶以 Iscover 的名義銷售,已使用一段時間以幫助預防血管成形術後的血栓,但新的結果可能會使其成為所有心臟病發作患者的標準。“這是自阿司匹林以來最好的訊息,”哈佛醫學院醫學助理教授克里斯托弗·P·坎農在《紐約時報》上評論道。“這真是一種名副其實的超級阿司匹林。”

Kate Wong is an award-winning science writer and senior editor at 大眾科學 focused on evolution, ecology, anthropology, archaeology, paleontology and animal behavior. She is fascinated by human origins, which she has covered for more than 25 years. Recently she has become obsessed with birds. Her reporting has taken her to caves in France and Croatia that Neandertals once called home, to the shores of Kenya's Lake Turkana in search of the oldest stone tools in the world, to Madagascar on an expedition to unearth ancient mammals and dinosaurs, to the icy waters of Antarctica, where humpback whales feast on krill, and on a "Big Day" race around the state of Connecticut to find as many bird species as possible in 24 hours. Kate is co-author, with Donald Johanson, of Lucy's Legacy: The Quest for Human Origins. She holds a bachelor of science degree in biological anthropology and zoology from the University of Michigan. Follow Wong on X (formerly Twitter) @katewong

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